HTML and CSS3 have many options to make great presentations. Although this, start a design from scratch and make presentations suitable for all screens is difficult. Zurb Foundation gives a full set of styles and utilities that helps to create a good design.
Zurb Foundation is written in SASS/SCSS, and can be used directly as CSS3. Currently it is used in many web pages and have a high degree of integration with jQuery.
The strong point of Zurb Foundation is that it can be configured quickly to create a corporative image in no time. It also can be personalized through graphic re-suable components.